ΠΑΣΤΕΡ

Δημοσιεύσεις - Προ-δημοσιεύσεις

1. Mirk/Dyrk1B Kinase Inhibitors in Targeted Cancer Therapy. Kokkorakis N, Zouridakis M, Gaitanou M. Pharmaceutics. 2024 Apr 11;16(4):528. doi: https://doi.org/10.3390/pharmaceutics16040528 . PMID: 38675189
2. Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson’s disease model with Lewy-like pathology. Christina Paschou, Olympia Apokotou, Anastasios Kollias, Konstantina Charmpi, Sofia Dede, Martina Samiotaki, Francesca Palese, Konstantina Dimoula, Evangelia Emmanouilidou, Era Taoufik, Chiara Zurzolo, Rebecca Matsas, Florentia Papastefanaki bioRxiv 2024.11.06.621638; doi: https://doi.org/10.1101/2024.11.06.621638 

Abstracts ομιλιών και posters σε Επιστημονικά Συνέδρια

1. Deciphering The Mechanisms of Early Synaptic Dysfunction in Parkinson’s Disease E.K. Akrioti1, K. Segklia1, K. Charmpi1, P. Koutsoudaki2, S. Chavaki2, S. Lipton3, R. Matsas1, E. Taoufik1 EMBO workshop _ Molecular Neurobiology _ Heraklion 13-17 May 2024
2. Deciphering & Targeting Early Synaptic Dysfunction in Pre-clinical Models of Parkinson’s disease E.K. Akrioti1, K. Segklia1, P. Chandris1, K. Charmpi1, A. Stavrou1, O. Apokotou1,2, F. Papastefanaki1,2, P. Koutsoudaki3, S. Chavaki3, S. Lipton4, R. Matsas1, E. Taoufik1 7th Congress of the Hellenic Society of Gene Therapy and Regenerative Medicine _ Thessaloniki 24-26 May 2024
3. SLITRK Dysregulation in Pre-Clinical Mouse and hipsc-Based Models of alpha-Synuclein Mediated Synaptopathy E.K. Akrioti1, P. Fourtini1, K. Segklia1, O. Apokotou1,2, Y. Pomeshchik3, F. Papastefanaki1,2, L. Roybon3,4, R. Matsas1, E. Taoufik1 ISSCR 2024_Hamburg 10-13 July 2024
4. Deciphering & Targeting Early Synaptic Dysfunction in Pre-clinical Models of Parkinson’s disease E.K. Akrioti1, K. Segklia1, P. Chandris1, K. Charmpi1, A. Stavrou1, O. Apokotou1,2, F. Papastefanaki1,2, P. Koutsoudaki3, S. Chavaki3, S. Lipton4, R. Matsas1, E. Taoufik1 7th Hellenic Pasteur Institute Young Scientists Conference 2024
5. Failure of major proteostatic mechanisms and lysosomal malfunction in p.A53T-αSyn PD patient iPSC-derived astrocytes [αναρτημένη ανακοίνωση] Paschou C, Dede S, Apokotou O, Dimoula K, Kollias A, Charmpi K, Samiotaki M, Zurzolo C, Emmanouilidou E, Taoufik E, Matsas R, Papastefanaki F Athens Conference on Advances in Chemistry, 6-8 November 2024
6. Paracrine Effects of Astrocytes on Neurons in an iPSC-derived Parkinson’s Disease Model With The p.A53T-αSyn Mutation Apokotou O, Dima D, Paschou C, Dede S, Kollias A, Taoufik E, Matsas, Papastefanaki F ISSCR Neural Stem Cell Symposium, Athens Greece, 3-4 April 2025
7. Investigating Senescence Phenotypes in Astrocytes Derived from p.A53T α-Synuclein PD- patient iPSCs [αναρτημένη ανακοίνωση] Paschou C, Sideris C.D, Dede S, Kollias A, Apokotou O, Taoufik E, Matsas R, Papastefanaki F Synuclein Meeting 2025, Cambridge UK, 8-11 April 2025
8. Investigating p.A53T-Alpha-Synuclein-Induced Astrocytic Senescence in a Parkinson’s disease induced pluripotent stem cell model Paschou C, Sideris C.D, Apokotou O, Dima E, Dede S, Kollias A, Taoufik E, Matsas R, Papastefanaki F The EMBO Workshop Astrocytes: From Molecules to Systems, Venice Italy, 14-18 April 2025
9. In vivo study of the effect of microglial BIN1 deletion in homeostatic and neuroinflammatory conditions (poster). Maria Margariti1*, Elsa Papadimitriou1#, Irini Thanou1#, Alexandre Pelletier2, Maria Anna Roussaki1, Evangelia Xingi3, Maria Avloniti4, Vasso Kyrargiri4, Marcos Costa5,6, Dimitra Thomaidou1. 30ο Συνέδριο της Ελληνικής Εταιρείας Νευροεπιστημών, 24-26 Νοεμβρίου 2023, ΕΚΕΦΕ Δημόκριτος, Αθήνα.
10. In vivo microglial Bin1 deletion following LPS stimulation regulates neuroinflammation in the mouse hippocampus and Adult Hippocampal Neurogenesis (poster). Maria Anna Roussaki1*, Maria Margariti1, Irini Thanou1, Evangelia Xingi2, Vasiliki Kyrargiri3, Marcos Costa4, 5, Dimitra Thomaidou1. Βραβείο καλύτερου πόστερ στην Ημερίδα Νέων Επιστημόνων 30ο Συνέδριο της Ελληνικής Εταιρείας Νευροεπιστημών, 24-26 Νοεμβρίου 2023, ΕΚΕΦΕ Δημόκριτος, Αθήνα.
11. Astrocyte reprogramming / activation and brain homeostasis (invited talk). Dimitra Thomaidou Πανελλήνιο Συνέδριο Βιοχημείας και Μοριακής Βιολογίας, 1-3 Δεκεμβρίου 2023, Ευγενίδειο Ιδρυμα, Αθήνα.
12. In vivo study of the effect of microglial BIN1 deletion in homeostatic and neuroinflammatory conditions (poster). Maria Margariti1*, Elsa Papadimitriou1#, Irini Thanou1#, Alexandre Pelletier2, Maria Anna Roussaki1, Evangelia Xingi3, Maria Avloniti4, Vasso Kyrargiri4, Marcos Costa5,6, Dimitra Thomaidou1. 73ο Πανελλήνιο Συνέδριο Βιοχημείας και Μοριακής Βιολογίας, 1-3 Δεκεμβρίου 2023, Ευγενίδειο Ιδρυμα, Αθήνα.
13. Control iPSC-derived astrocytes rescue p.A53T-αSyn patient-iPSC-derived neurons from Parkinson’s disease-related pathology [προφορική ανακοίνωση] Olympia Apokotou, Sofia Dede, Christina Paschou, Anastasios Kollias, Konstantina Charmpi, Martina Samiotaki, Era Taoufik, Chiara Zurzolo, Rebecca Matsas, Florentia Papastefanaki 7th Hellenic Pasteur Institute Young Scientists Conference, Athens 17-18 October 2024
14. Failure of major proteostatic mechanisms in p.A53T-αSyn PD patient iPSC-derived astrocytes, due to lysosomal malfunction [αναρτημένη ανακοίνωση] Christina Paschou, Sofia Dede, Anastasios Kollias, Konstantina Charmpi, Olympia Apokotou, Martina Samiotaki, Chiara Zurzolo, Era Taoufik, Rebecca Matsas, Florentia Papastefanaki 7th Hellenic Pasteur Institute Young Scientists Conference, Athens 17-18 October 2024
15. Study of cellular senescence phenotypes in astrocytes derived from Parkinson’s Disease patient-iPSCs [αναρτημένη ανακοίνωση] Constantinos D. Sideris, Christina Paschou, Sofia Dede, Anastasios Kollias, Era Taoufik, Rebecca Matsas, Florentia Papastefanaki 7th Hellenic Pasteur Institute Young Scientists Conference, Athens 17-18 October 2024
16. Metabolic impairment in PD-patient iPSC-derived p.A53T-αSyn astrocytes [αναρτημένη ανακοίνωση] Evanthia Tselo, Anastasios Kollias, Christina Paschou, Era Taoufik, Rebecca Matsas, Florentia Papastefanaki 7th Hellenic Pasteur Institute Young Scientists Conference, Athens 17-18 October 2024
17. Proteostasis Deficiency in iPSC-derived Astrocytes Exacerbates Neurodegeneration in a Model of Early Onset PD from A53T alpha-Synuclein Patients [αναρτημένη ανακοίνωση] Christina Paschou, Olympia Apokotou, Anastasios Kollias, Konstantina Charmpi, Sofia Dede, Martina Samiotaki, Era Taoufik, Chiara Zurzolo, Rebecca Matsas, Florentia Papastefanaki ISSCR 2024 Hamburg 10-13 July 2024
18. Control iPSC-derived astrocytes rescue p.A53T-αSyn patient-iPSC-derived neurons from Parkinson’s disease-related pathology [προφορική ανακοίνωση] Olympia Apokotou, Sofia Dede, Christina Paschou, Anastasios Kollias, Konstantina Charmpi, Martina Samiotaki, Era Taoufik, Chiara Zurzolo, Rebecca Matsas, Florentia Papastefanaki 7th Congress of the Hellenic Society of Gene Therapy and Regenerative Medicine, Thessaloniki 24-26 May 2024
19. 19. Investigating p.A53T-Alpha-Synuclein-Induced Astrocytic Senescence in a Parkinson’s disease induced pluripotent stem cell model Paschou C, Sideris C.D, Apokotou O, Dima E, Dede S, Kollias A, Taoufik E, Matsas R, Papastefanaki F ISSCR Neural Stem Cell Symposium, Athens Greece, 3-4 April 2025
20. In vivo study of the effect of microglial BIN1 deletion on mouse brain under homeostatic and neuroinflammatory conditions (poster). Maria Margariti1*, Elsa Papadimitriou1#, Irini Thanou1#, Alexandre Pelletier2, Maria Anna Roussaki1, Evangelia Xingi3, Maria Avloniti4, Vasso Kyrargiri4, Marcos Costa5,6, Dimitra Thomaidou1. EMBO workshop "Microglia in health and disease", 21-24 May 2024, Genoa, Italy.
21. In vivo microglial Bin1 deletion regulates neuroinflammation and Adult Neurogenesis in the mouse hippocampus (poster) Irini Thanou, Maria Anna Roussaki, Maria Margariti, Evangelia Xingi, Marcos Costa, Dimitra Thomaidou. EMBO workshop "Microglia in health and disease", 21-24 May 2024, Genoa, Italy.
22. Ιn vivo study of the effect of microglial BIN1 deletion on mouse brain under homeostatic and neuroinflammatory conditions (talk). Maria Margariti1, Elsa Papadimitriou1*, Irini Thanou1*, Alexandre Pelletier2, Evangelia Xingi3, Maritsa Margaroni4, Vasiliki Kyrargyri5, Marcos Costa6,7, Dimitra Thomaidou1. 7ο Συνέδριο Νέων Επιστημόνων Ελληνικού Ινστιτούτου Παστέρ, 17-18 Οκτωβρίου, ΕΙΠ, Αθήνα.
23. In vivo microglial Bin1 deletion regulates neuroinflammation and Adult Neurogenesis in the mouse hippocampus (poster). Irini Thanou1, Maria Anna Roussaki1, Maria Margariti1, Evangelia Xingi3, Marcos Costa2,4, Dimitra Thomaidou1. Βραβείο καλύτερου πόστερ 7ο Συνέδριο Νέων Επιστημόνων Ελληνικού Ινστιτούτου Παστέρ, 17-18 Οκτωβρίου, ΕΙΠ, Αθήνα.
24. Elucidation of the miR-124/ISX9-mediated transcriptional mechanism instructing the cell fate switch of astrocytes to induced-neurons (poster).     Elsa Papadimitriou, Alexandra Frazescou, Lukas daCC Iohan, Marcos R Costa, D. Thomaidou ΙSSCR International Symposium: «Neural Stem Cells: Capturing Complexity and Plasticity from the Cell to the Organism» π, 3-4 Απριλίου 2025
25. Alzheimer’s Disease risk factor BIN1: Linking microglial deficiency to neuroinflammation and regulation of Adult Hippocampal Neurogenesis (poster) Irini Thanou, Maria Anna Roussaki, Maria Margariti, Elsa Papadimitriou, Evangelia Xingi, Maritsa Margaroni, Marcos Costa, Dimitra Thomaidou ΙSSCR International Symposium: «Neural Stem Cells: Capturing Complexity and Plasticity from the Cell to the Organism», 3-4 Απριλίου 2025
26. Expression, isolation, and characterization of recombinant full binding sites of the human neuronal nicotinic acetylcholine receptor (poster). Kordela Anna, Marios Zouridakis, Aikaterini I. Argyriou, Georgios A. Spyroulias, Elias Eliopoulos and Petros Giastas 73ο Πανελλήνιο Συνέδριο της ΕΕΒΜΒ